mTORC1

mTORC1 (mechanistic target of rapamycin complex 1) is a protein complex central to regulating cell growth and metabolism; it integrates signals from nutrients, growth factors, and energy levels to control protein synthesis and autophagy; when activated by certain lipids like omega-6 linoleic acid, it can drive excessive cell proliferation, contributing to diseases such as cancer; understanding its regulation is key to developing targeted therapies for various cancers.